36 Northwest players were drafted on the second day of the major league draft of college and high school players—including 20 Baseball Northwest alumni. The draft will end on Thursday with the last 20 rounds. * indicates Baseball Northwest alumni.
| Round | Team | Overall | Name | Position | B/T | Height | Weight | School |
| 4TH | METS | #134 | DARELL CECILIANI | OF | L/L | 6′0 | 185 | COLUMBIA BASIN CC |
| 4TH | PHILLIES | #167 | MATTHEW WAY | LHP | L/L | 6′2 | 200 | WASHINGOTN STATE |
| 6TH | A’S | #183 | RYAN ORTIZ | C | R/R | 6′3 | 205 | OREGON STATE |
| 7TH | ROCKIES | #211 | ERIC STAVERT | RHP | R/R | 6′2 | 185 | UNIVERSITY OF OREGON |
| 7TH | CARDINALS | #219 | KYLE CONLEY | OF | R/R | 6′4 | 215 | UNIVERSITY OF WASHINGTON |
| 7TH | BLUE JAYS | #220 | EGAN SMITH | LHP | L/L | 6′5 | 200 | COLLEGE OF SOUTHERN IDAHO |
| 8TH | RANGERS | #244 | BRADEN TULLIS | RHP | R/R | 6′2 | 200 | SKAGIT VALLEY CC |
| 9TH | REDS | #269 | BRIAN PEARL* | RHP | R/R | 6′1 | 190 | UNIVERSITY OF WASHINGTON |
| 10TH | DBACKS | #306 | TYSON VAN WINKLE* | C | R/R | 601 | 185 | GONZAGA UNIVERSITY |
| 10TH | ANGELS | #321 | JAKE LOCHER* | OF | R/R | 6′3 | 225 | UNIVERSITY OF WASHINGTON |
| 11TH | CLEVELAND | #335 | KIRK WETMORE* | LHP | L/L | 6′2 | 205 | BELLEVUE CC |
| 13TH | CLEVELAND | #395 | JEREMY JOHNSON* | RHP | R/R | 5′11 | 185 | WASHINGTON STATE |
| 13TH | MARLINS | #398 | TYLER CURTIS | RHP | R/R | 6′3 | 230 | COLLEGE OF SOUTHERN IDAHO |
| 13TH | BREWERS | #406 | SEAN HALTON | OF | R/R | 6′5 | 245 | LEWIS-CLARK STATE |
| 14TH | A’S | #423 | DREW GAGNIER | RHP | R/R | 6′4 | 225 | UNIVERSITY OF OREGON |
| 15TH | A’S | #443 | BLAKE KEITZMAN* | LHP | L/L | 6′0 | 185 | WESTERN OREGON |
| 17TH | PADRES | #504 | JORGE REYES | RHP | R/R | 6′3 | 195 | OREGON STATE |
| 17TH | DODGERS | #517 | STEVE AMES* | RHP | R/R | 6′0 | 205 | GONZAGA UNIVERSITY |
| 17TH | RED SOX | #528 | KRAIG SITTON* | LHP | L/L | 6′5 | 190 | OREGON STATE |
| 18TH | RAYS | #559 | JACOB PARTRIDGE* | LHP | L/L | 6′3 | 185 | ROGERS HS |
| 20TH | METS | #614 | JOEY AUGUST* | OF | L/L | 6′1 | 200 | STANFORD UNIVERSITY |
| 22ND | BLUE JAYS | #670 | MATTHEW FIELDS | RHP | R/R | 6′3 | 190 | GONZAGA UNIVERSITY |
| 23RD | MARLINS | #698 | THOMAS PEALE | RHP | R/R | 6′3 | 225 | LEWIS-CLARK ST. |
| 24TH | PIRATES | #715 | JASON ERICKSON* | RHP | R/R | 6′0 | 195 | UNIVERSITY OF WASHINGTON |
| 24TH | GIANTS | #717 | ALEX BURG* | C | R/R | 6′0 | 190 | WASHINGTON STATE |
| 24TH | ROCKIES | #721 | JOEY WONG* | SS | L/R | 5′10 | 175 | OREGON STATE |
| 24TH | A’S | #723 | DAN STRAILY | RHP | R/R | 6′2 | 230 | MARSHALL UNIVERSITY |
| 25TH | TWINS | #762 | TONY BRYANT | RHP | R/R | 6′7 | 210 | KENNEWICK HS |
| 25TH | RAYS | #769 | RYAN WIEGLAND | 1B | L/L | 6′4 | 225 | GONZAGA UNIVERSITY |
| 27TH | BLUE JAYS | #820 | BRIAN JUSTICE* | RHP | R/R | 6′2 | 190 | ST. MARY’S UNIVERSITY |
| 27TH | MARLINS | #818 | NATE SIMON* | 2B | L/R | 6′3 | 195 | PEPPERDINE UNIVERSITY |
| 28TH | ROYALS | #842 | ERIC PETERSON* | SS | L/R | 6′3 | 195 | LIBERTY HS |
| 28TH | RAYS | #859 | ZACH ROSSCUP* | LHP | L/L | 6′2 | 205 | CHEMEKETA CC |
| 29TH | REDS | #869 | JASON BRAUN* | RHP | R/R | 6′5 | 185 | CORBAN COLLEGE |
| 29TH | ANGELS | #891 | WILLIAM NICHOLLS | RHP | R/R | 6′2 | 180 | COLLEGE OF SOUTHERN IDAHO |
| 30TH | TIGERS | #900 | JAMES ROBBINS* | 1B | L/L | 6′0 | 225 | SHORECREST HS |
